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For example, engineered bacteria enhance radiation therapy by targeting tumour hypoxia, delivering radiosensitizers, and bridging radiation with immunotherapy via bacterial components to stimulate systemic antitumor immunity (Pan et al., 2022)

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Scenario prediction using bioinformatics tools has shown that the sequences of miRNAs and their changes over time determine how they interact with their targets (candidate mRNAs).[48] The genetic diversity of tumors and cell lines produced by different malignancies makes evaluating the association between a particular miRNA and specific cancer difficult