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"A novel single nucleotide polymorphism in the 3' untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism"

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In 1992 it was demonstrated that a group of 289 subjects with workplace chemical exposure had quantitative and qualitative alterations at the cellular level (T and B lymphocytes and NK cells), such as abnormal T4/T8 ratios, elevated T cell (CD3 + ) and B cell (CD19 + ) numbers, activated T cells (CD10 + , CD15 + , CD26 + , CD38 + ), suppressed T cell and B cell function, and abnormal NK cell cytotoxic activity