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PNPLA3 G-allele was associated with fibrosis (adj.HR for ≥1 point: 1.8, 95% CI: 1.2-2.7, and for ≥2 points: 1.6, 95% CI: 1.02-3.04) and MASH (adj.HR: 2.4, 95% CI: 1.5-3.9) progression, and a lower likelihood of MASH resolution (adj.HR: 0.61, 95% CI: 0.39-0.95) after adjusting for relevant confounders
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