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Single-cell studies are beginning to decipher these differences ( An emerging concept is the “digital twin” for aging, a computational model of a patient that can predict how they would respond to various interventions ( Table 1 summarizes recent single-cell multi-omics findings across cardiovascular and aging contexts and links key cell states to potential clinical uses

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This difference in reaction, combined with the knowledge of vycross technology, merits the question of whether certain filler properties interact more with the immune system to be more immunogenic [75]

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